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Diabetic Retinopathy Disease

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Diabetic Retinopathy Treatment

Diabetic Retinopathy Disease

Diabetic retinopathy is a complication of diabetes that affects the eyes. It is caused by damage to the blood vessel light-sensitives of the tissue (retina) at the back of the eye.
Initially, diabetic retinopathy may cause no symptoms or only mild vision problems. But it can go as far as blindness.The condition can develop in anyone with type 1 or type 2 diabetes. The longer you have diabetes and the less your blood sugar is controlled, the more likely you are to develop this eye complication.


In the early stages of diabetic retinopathy, you may not have symptoms. As the condition progresses, you may develop:

  • Floating spots or dark bands (flyers) in your vision.
  • Blurred vision.
  • Wavy vision.
  • Dark or blank areas in your vision.
  • Vision loss.

When you should see your doctor

Careful management of your diabetes is the best way to prevent vision loss. Especially, if you have diabetes, see your eye doctor for an annual eye exam, even if your vision looks good.

Particularly, developing diabetes while pregnant (gestational diabetes) or having diabetes before becoming pregnant can increase your risk of diabetic retinopathy. If you are pregnant, your eye doctor may recommend additional eye exams throughout your pregnancy.

Also, contact your eye doctor right away if your vision suddenly changes or becomes blurry, spotty or hazy.

Causes of the Disease

Over time, having too much sugar in your blood can cause the tiny blood vessels that feed the retina to become clogged and cut off blood flow. As a result, the eye tries to form new blood vessels. But these new blood vessels do not develop properly and can leak easily.

There are two types of diabetic retinopathy:

Early diabetic retinopathy.

In this more common form, call non-proliferative diabetic retinopathy (NPDR), new blood vessels do not grow (proliferate).

Especially, when you have NPDR, the walls of the blood vessels in your retina weaken. Small projections protruding from the walls of small vessels, sometimes leaking fluid and blood into the retina. Larger retinal vessels may also begin to dilate and become irregular in diameter. NPDR can progress from mild to severe as more blood vessels become blocked.

Sometimes retinal blood vessel damage leads to fluid buildup (edema) in the central part of the retina (macula). If macular edema reduces vision, treatment is require to prevent permanent vision loss.

Advanced diabetic retinopathy.

Especially, diabetic retinopathy can progress to this more severe type known as proliferative diabetic retinopathy. In this type, damaged blood vessels close, causing new, abnormal blood vessels to grow in the retina. These new blood vessels are fragile and can leak into the clear, jelly-like substance that fills the center of your eye (the vitreous).

Eventually, scar tissue from the growth of new blood vessels can cause the retina to detach from the back of the eye. Also, pressure can build up in the eyeball if new blood vessels interfere with the normal flow of fluid in the eye. Therefore, this buildup can cause glaucoma by damaging the nerve (optic nerve) that carries images from your eye to the brain.

Risk factors

Anyone with diabetes can develop diabetic retinopathy. The risk of developing an eye condition may be increased as a result of:

  • Having been diabetic for a long time.
  • Poor control of your blood sugar level.
  • High blood pressure.
  • High cholesterol.
  • Pregnancy.
  • Smoking use.


Diabetic retinopathy involves the growth of abnormal blood vessels in the retina. Complications can lead to serious vision problems:

Vitreous hemorrhage.

Particularly, new blood vessels can bleed into the clear, jelly-like substance that fills the center of your eye. If the amount of bleeding is small, you may only see a few dark spots (flying objects). In more severe cases, blood can fill the vitreous cavity and completely block your vision.

Vitreous hemorrhage alone does not usually cause permanent vision loss. The blood usually clears from the eye within a few weeks or months. Unless your retina is damaged, your vision will likely return to its former clarity.

Retinal detachment:

The abnormal blood vessels associated with diabetic retinopathy stimulate the growth of scar tissue, which can pull the retina away from the back of the eye. Also, this can cause floating spots in your vision, flashes of light, or severe vision loss.


New blood vessels can grow in the front of your eye (iris) and block the normal flow of fluid in the eye. Therefore this is causing pressure in the eye. Also, this pressure can damage the nerve (optic nerve) that carries images from your eye to the brain.


Particularly, diabetic retinopathy, macular edema, glaucoma, or a combination of these conditions can cause complete vision loss. Especially if the conditions are poorly manage.

Prevention from Disease

Generally, you can’t always prevent diabetic retinopathy. However, regular eye exams, good control of your blood sugar and blood pressure, and early intervention for vision problems can help prevent serious vision loss.

If you have diabetes, reduce your risk of developing diabetic retinopathy by doing the following:

Manage your diabetes. Make healthy eating and physical activity part of your daily routine. Try to do at least 150 minutes of moderate aerobic activity, such as walking, each week. Take diabetes medications or insulin as directed.

Monitor your blood sugar level. Also, you may need to check and record your blood sugar levels several times a day or more often if you are sick or under stress. Ask your doctor how often you should test your blood sugar.

Also, ask your doctor about the glycosylated hemoglobin test. Specifically, the glycosylated hemoglobin test, or hemoglobin A1C test, reflects your average blood sugar level for the two to three months before the test. For most people with diabetes, the A1C goal is to be below 7%.

Especially, keep your blood pressure and cholesterol under control. Eating healthy foods, exercising regularly, and shedding extra pounds can help. Sometimes medication is also needed.

Moreover, if you smoke or use other forms of tobacco, seek help from your doctor to quit. Especially, smoking increases your risk of various diabetes complications, including diabetic retinopathy.

Pay attention to vision changes. Particularly, if your vision suddenly changes or becomes blurry, mottled or hazy, contact your eye doctor right away.

Remember, diabetes does not necessarily lead to vision loss. Therefore, taking an active role in diabetes management can go a long way in preventing complications.

Diagnosis of the Disease

Diabetic retinopathy can be diagnose with a comprehensive eye exam. The drops place in your eyes for this examination will enlarge (dilate) your pupils and allow your doctor to see inside your eyes better.

During the exam, your eye doctor will look for abnormalities in the inner and outer parts of your eyes.

Fluorescent Angiography

After your eyes are open, dye is injected into a vein in your arm. Pictures are then taken as the dye travels through the blood vessels of your eyes. Images can pinpoint closed, broken, or leaky blood vessels.

Optical coherence tomography (OCT)

With this test, pictures provide cross-sectional images that show the thickness of the retina. This will help determine how much fluid, if any, is leaking into the retinal tissue. It will then be follow up with OCT tests to monitor how the treatment is progressing.

Treatment of the Disease

Treatment, which depends largely on the type of diabetic retinopathy you have and how severe it is, is aimed at slowing or stopping the progression.

Early Diabetic Retinopathy Treatment

If you have mild or moderate non-proliferative diabetic retinopathy, you may not need treatment right away. However, your eye doctor will watch your eyes closely to determine when you may need treatment.

Work with your diabetes doctor (endocrinologist) to determine if there are ways to improve your diabetes management. When diabetic retinopathy is mild or moderate, good blood sugar control can often slow progression.

Advanced Diabetic Retinopathy Treatment

If you have proliferative diabetic retinopathy or macular edema, you will need emergency treatment. Depending on specific problems with your retina, options may include:

Injecting medication into the eye. These drugs, call vascular endothelial growth factor inhibitors, are inject into the vitreous of the eye. They help stop the growth of new blood vessels and reduce fluid buildup.

These drugs are injecting with topical anesthetic. Injections may cause mild discomfort such as burning, tearing or pain 24 hours after injection.

These injections will need to be repeatedly. In some cases, the drug is use in combination with photocoagulation.


Also known as focal laser therapy, this laser therapy can stop or slow the leakage of blood and fluid in the eye. Leakages from abnormal blood vessels during the procedure are treat with laser burns.

Focal laser therapy

It’s usually apply in a single session at your doctor’s office or eye clinic. If you had blurred vision from macular edema prior to surgery, treatment may not return your vision to normal, but it will likely reduce the chance of your macular edema worsening.

Panretinal photocoagulation

Also known as scatter laser therapy, this laser treatment can shrink abnormal blood vessels. During the procedure, areas of the retina distal to the macula are treat with scattered laser burns. Burns cause abnormal new blood vessels to shrink and scar.

Particularly, these procedures are done in two or more sessions at the Eye Clinic in a hospital. Also, your vision will be blurry about a day after the procedure. Although, some loss of peripheral vision or night vision is possible after the procedure.

Vitrectomy Surgery

This procedure uses a small incision in your eye to remove blood from the middle of the eye (vitreus) and scar tissue that draws the retina. Also, it is perform in a surgery center or hospital using local or general anesthesia.

Especially, treatment can slow or stop the progression of diabetic retinopathy, but it is not a cure. Because diabetes is a lifelong condition, retinal damage and vision loss are still possible in the future.

More importantly, you will still need regular eye exams even after diabetic retinopathy treatment. Also, at some point, you may need additional treatment.

Useful Links

About Eye Uveal Melanoma – Eye Cancer Treatment, Vitrectomy Retina Surgeries, About Keratoplasty Surgery Strabismus Crossed Eye Squint Treatments, Macular Degeneration Treatments. Glaucoma Disease and Treatments. Retinitis Pigmentosa Disease and Treatments. Dry Eye Syndrome Treatments. Periodic Eye Examinations.

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Prof. Dr. Fevzi Şentürk, Göz Doktoru, Retina uzmanı, Our eye doctors, göz Doktorlarımız, Göz cerrahlarımız

Prof.Dr. Fevzi Senturk

Education Information:

He completed his primary, secondary and high school education in Ankara. Fevzi Senturk graduated from Ankara University Faculty of Medicine with a degree in 1994, and subsequently received his Ophthalmology Specialization training from Eskisehir Osmangazi University Faculty of Medicine in 2000. Afterwards, Fevzi Senturk completed his Retina Fellowship at Istanbul Retina Institute and earned the title of Associate Professor at this institution. He is still continuing his academic career by taking the title of Professor at Istanbul Medipol University. He has focused his scientific and clinical studies on retinal diseases, Vitreoretinal surgery and cataract surgery.

Awards,Memberships and Scientific Research:

  • Retinal capillary hemangioma: AB interno surgical excision, 43rd National Congress Awards, Best Video First Prize, 2009
  • Photodynamic therapy guided by indocyanine green angiography in chronic central serous chorioretinopathy, Turkish Journal of Ophthalmology, Best Publication Third Prize, 2000
  • Retinal capillary hemangioma: AB interno surgical excision, 43rd National Congress Awards, Best Video First Prize, 2009
  • Photodynamic therapy guided by indocyanine green angiography in chronic central serous chorioretinopathy, Turkish Journal of Ophthalmology, Best Publication Third Prize, 2000
  • Vitreoretinal Surgery Techniques, Second Edition, Hayat Medicine Bookstore, 2008
  • Eye Diseases and Anti-VEGF Therapy 2010.
  • Ocular Electrophysiology (TOD Education Publications No 13) Meaning of VEP, VEP registration and parameters in ISCEV standards., 2011
  • Clinical Eye Atlas (Oxford Atlases in Ophthalmology), 2012
  • Imaging in Ophthalmology, Microperimetry, 2013
  • Ocular Electrophysiology (TOD Education Publications 1st Edition), Multifocal Electroretinogram Recording and Evaluation, 2022.
  • Current Vitreoretinal Surgery (TOD Education Publications), Surgical Anatomy of the Retinal and Vitreous, 2022.
  • Turkish Medical Association
  • Turkish Ophthalmology Association
  • Turkic Republics Ophthalmology Association
  • Electrodiagnostic unit board membership
  • Electrodiagnostic unit training representative
  • International Society for Clinical Electrophysiology of Vision (ISCEV)

Specialized Treatments and Surgeries:

  • Macular Degeneration Disease and Treatments
  • Retinal Detachment Treatments
  • Retinal Hemorrhages Due to Diabetes and Hypertension and Their Treatments
  • Retinitis Pigmentosa Treatments
  • Central Serous Chorioretinopathy
  • Retinal Vascular Occlusions
  • Epirentinal Membrane
  • Macular Hole
  • Glaucoma eye pressure
  • Neuroophthalmological Diseases
  • Vitrectomy-Retina Surgery
  • Intravitreal Injection Treatments
  • Argon Laser Photocoagulation Treatment
  • Photodynamic Therapies

Foreign language:

  • English
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